Detalhe da pesquisa
1.
Antinociceptive Effect of Dillenia indica (Linn.) Mediated by Opioid and Cannabinoid Systems: Pharmacological and Chemical Studies.
Chem Biodivers
; 21(3): e202301508, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092696
2.
Chemical Composition, Anthelmintic Activity, and Mechanism of Action of Lippia dominguensis Mold. Essential Oil on Haemonchus contortus.
Chem Biodivers
; 20(7): e202300135, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37172262
3.
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease.
Bioorg Med Chem
; 71: 116952, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35930852
4.
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases.
Neurochem Res
; 45(12): 3003-3020, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33079324
5.
New multifunctional AChE inhibitor drug prototypes protect against Aß-induced memory deficit.
Neurol Sci
; 41(2): 451-455, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31506829
6.
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease.
Molecules
; 25(14)2020 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32664425
7.
The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.
Molecules
; 23(7)2018 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30037040
8.
In vitro evaluation of the schistosomicidal effect of the extracts, fractions and major 3-hydroxy-2,6-dialkyl-substituted piperidine alkaloids from the flowers of Senna spectabilis (Fabaceae).
Bioorg Med Chem Lett
; 26(17): 4197-204, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27491706
9.
Testing the methodology for dosimetry audit of heterogeneity corrections and small MLC-shaped fields: Results of IAEA multi-center studies.
Acta Oncol
; 55(7): 909-16, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26934916
10.
Synthesis and biological evaluation of novel piperidine-benzodioxole derivatives designed as potential leishmanicidal drug candidates.
Bioorg Med Chem Lett
; 25(16): 3346-9, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26094119
11.
Multi-Target Directed Drugs: A Modern Approach for Design of New Drugs for the treatment of Alzheimer's Disease.
Curr Neuropharmacol
; 12(3): 239-55, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24851088
12.
Synthesis and biological evaluation against Leishmania amazonensis of a series of alkyl-substituted benzophenones.
Bioorg Med Chem
; 21(11): 3114-9, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23623672
13.
Piperine-Chlorogenic Acid Hybrid Inhibits the Proliferation of the SK-MEL-147 Melanoma Cells by Modulating Mitotic Kinases.
Pharmaceuticals (Basel)
; 16(2)2023 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37259298
14.
A synthetic resveratrol-curcumin hybrid derivative exhibits chemopreventive effects on colon pre-neoplastic lesions by targeting Wnt/ß-catenin signaling, anti-inflammatory and antioxidant pathways.
J Pharm Pharmacol
; 2023 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37874746
15.
Semisynthesis and antimicrobial activity of novel guttiferone-A derivatives.
Bioorg Med Chem
; 20(8): 2713-20, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22401914
16.
The genus Caesalpinia L. (Caesalpiniaceae): phytochemical and pharmacological characteristics.
Molecules
; 17(7): 7887-902, 2012 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22751225
17.
Curcumin, Resveratrol and Cannabidiol as Natural Key Prototypes in Drug Design for Neuroprotective Agents.
Curr Neuropharmacol
; 20(7): 1297-1328, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825873
18.
Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
RSC Med Chem
; 13(5): 568-584, 2022 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35694691
19.
Phytocannabinoids: General Aspects and Pharmacological Potential in Neurodegenerative Diseases.
Curr Neuropharmacol
; 19(4): 449-464, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32691712
20.
Alzheimer's Disease: Related Targets, Synthesis of Available Drugs, Bioactive Compounds Under Development and Promising Results Obtained from Multi-target Approaches.
Curr Drug Targets
; 22(5): 505-538, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814524